Resveratrol (trans-3, 5, 4'-trihydroxystilbene), a compound found largely in the skins of red grapes, is a component of Ko-jo-kon, an oriental medicine used to treat diseases of the blood vessels, heart [1, 2], and liver [2]. It came to scientific attention only four years ago, however, as a possible explanation for the "French Paradox" -- the low incidence of heart disease among the French people, who eat a relatively high-fat diet [3]. Today, it is touted by manufacturers and being examined by scientific researchers as an antioxidant [4], an anti-cancer agent, and a phytoestrogen [5]. It is also being advertised on the Internet as "The French Paradox in a bottle." [A] Arkopharma, of Wallingford, Connecticut, even markets a red-wine extract antioxidant product called "French Parad'ox." This article reviews the recent research on resveratrol's physiologic activity.